Reduction in Wound Bioburden using a Silver-Loaded Dissolvable Microfilm Construct
نویسندگان
چکیده
منابع مشابه
Silver dressings improve diabetic wound healing without reducing bioburden.
UNLABELLED Introduction. Silver dressings are widely used in the treatment of chronic wounds to reduce bacterial bioburden. However, little is known about the mechanism of silver ions on the healing process. In this study, a mouse model of wound healing was used to examine the effect of silver dressings in normal and diabetic wounds. METHODS Two 5-mm full-thickness wounds were created on t...
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Microbial bioburden in both acute and chronic wounds is an important factor in wound healing. Consequently, the reduction of bioburden to host-manageable levels, as well as the elimination of certain virulent forms of wound pathogens (regardless of their number), has become a goal of the wound care professional. A prospective, controlled clinical study using accepted sampling methods was conduc...
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Modern wound management requires that systematic assessment and treatment approaches be adopted in order to address the needs of the wound in a logical way. The frameworks of wound bed preparation using the TIME acronym (Dowsett and Ayello, 2004) and Applied Wound Management (Gray et al, 2006) are two such systems. Both require the assessment and management of the tissues in the wound (e.g. slo...
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OBJECTIVE To determine the in vivo effect of a sustained-release silver sulphadiazine powder foam dressing on the bacterial burden of venous leg ulcers (VLUs), with a view to correlating the wound closure rate with the degree of bioburden and to assess other markers of its progression towards healing. METHOD Patients attending a tertiary care wound practice were screened for a VLU bacterial c...
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The nanofibrous biodegradable drug-loaded membranes that sustainably released recombinant human platelet-derived growth factor (rhPDGF-BB) to repair diabetic wounds were developed in this work.rhPDGF-BB and poly(lactic-co-glycolic acid) (PLGA) were mixed in hexafluoroisopropyl alcohol, followed by the electrospinning of the solutions into biodegradable membranes to equip the nanofibrous membran...
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ژورنال
عنوان ژورنال: Advanced Healthcare Materials
سال: 2014
ISSN: 2192-2640
DOI: 10.1002/adhm.201300537